Default header image






Case Studies in Physiology: Sympathetic neural discharge patterns in a healthy young male during end-expiratory breath hold-induced sinus pause. Vermeulen TD, Shafer BM, Incognito AV, Nardone M, Teixeira AL, Millar PJ, Shoemaker JK, Foster GE. J Appl Physiol. 2020 Jul 9. doi: 10.1152/japplphysiol.00307.2020.

Within-breath sympathetic baroreflex sensitivity is modulated by lung volume but unaffected by acute intermittent hypercapnic hypoxia in men. Nardone M, Teixeira AL, Incognito AV, Vermeulen TD, Shafer BM, Millar PJ, Foster GE. Am J Physiol Heart Circ Physiol. 2020 Jul 1;319(1):H213-H221. doi: 10.1152/ajpheart.00296.2020. Epub 2020 Jun 5.

Looking beyond the mean: Are racial differences in beat-to-beat blood pressure variability among young men a harbinger for future cardiovascular risk? Millar PJ. Exp Physiol. 2020 Jul;105(7):1055-1057. 

New insights into the complexity of arterial baroreflex control of muscle sympathetic outflow in humans. Incognito AV, Millar PJ. J Physiol. 2020 May;598(10):1803-1804.

Physical Activity to Prevent and Treat Hypertension: A Systematic Review. Smart NA, Howden R, Cornelissen V, Brook R, McGowan C, Millar PJ, Ritti-Dias R, Baross A, Carlson DJ, Wiles JD, Swaine I. Med Sci Sports Exerc. 2020 Apr;52(4):1001-1002. 

Arterial baroreflex regulation of muscle sympathetic single-unit activity in men: influence of resting blood pressure. Incognito AV, Samora M, Shepherd AD, Cartafina RA, Guimarães GMN, Daher M, Millar PJ, Vianna LC. Am J Physiol Heart Circ Physiol. 2020 Apr 1;318(4):H937-H946.


Arterial baroreflex regulation of muscle sympathetic nerve activity at rest and during stress.
Incognito AV, Duplea SG, Lee JB, Sussman J, Shepherd AD, Doherty CJ, Cacoilo JA, Notay K, Millar PJ. J Physiol. 2019 Sep;597(18):4729-4741.

Effects of dynamic arm and leg exercise on muscle sympathetic nerve activity and vascular conductance in the inactive leg.
Doherty CJ, King TJ, Incognito AV, Lee JB, Shepherd AD, Cacoilo JA, Slysz JT, Burr JF, Millar PJ. J Appl Physiol. 2019 Aug 1;127(2):464-472.

Docosahexaenoic acid reduces resting blood pressure but increases muscle sympathetic outflow compared with eicosapentaenoic acid in healthy men and women.
Lee JB, Notay K, Klingel SL, Chabowski A, Mutch DM, Millar PJ. Am J Physiol Heart Circ Physiol. 2019 Apr 1;316(4):H873-H881.

Microneurographic characterization of sympathetic responses during 1-leg exercise in young and middle-aged humans.
Notarius CF, Millar PJ, Doherty CJ, Incognito AV, Haruki N, O’Donnell E, Floras JS. Appl Physiol Nutr Metab. 2019 Feb;44(2):194-199.

Cardiovascular responses during isometric exercise following lengthening and shortening contractions.
Seed JD, St Peters B, Power GA, Millar PJ. J Appl Physiol. 2019 Feb 1;126(2):278-285.

Evidence for differential control of muscle sympathetic single units during mild sympathoexcitation in young, healthy humans.
Incognito AV, Doherty CJ, Nardone M, Lee JB, Notay K, Seed JD, Millar PJ. Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H13-H23.

Pharmacological assessment of the arterial baroreflex in a young healthy obese male with extremely low baseline muscle sympathetic nerve activity.
Incognito AV, Samora M, Cartafina RA, Guimarães GMN, Daher M, Millar PJ, Vianna LC. Clin Auton Res. 2018 Dec;28(6):593-595.

Blunted Cardiac Output from Overtraining Is Related to Increased Arterial Stiffness.
Coates AM, Millar PJ, Burr JF. Med Sci Sports Exerc. 2018 Dec;50(12):2459-2464.

Left Ventricular Structure and Function in Elite Swimmers and Runners.
Currie KD, Coates AM, Slysz JT, Aubry RL, Whinton AK, Mountjoy ML, Millar PJ, Burr JF. Front Physiol. 2018 Nov 28;9:1700.

TRPV1 and BDKRB2 receptor polymorphisms can influence the exercise pressor reflex.
Notay K, Klingel SL, Lee JB, Doherty CJ, Seed JD, Swiatczak M, Mutch DM, Millar PJ. J Physiol. 2018 Nov;596(21):5135-5148. Accompanying editorial

Hypertensive Response With Exercise to Reveal Increased Cardiovascular Risk in Adults With Aortic Coarctation Repair: Value and Caution.
Millar PJ, Oechslin EN. Can J Cardiol. 2018 May;34(5):536-539.

Three Weeks of Overload Training Increases Resting Muscle Sympathetic Activity.
Coates AM, Incognito AV, Seed JD, Doherty CJ, Millar PJ, Burr JF. Med Sci Sports Exerc. 2018 May;50(5):928-937.

2019 Collaborative Papers

Training heart failure patients with reduced ejection fraction attenuates muscle sympathetic nerve activation during mild dynamic exercise.
Notarius CF, Millar PJ, Keir DA, Murai H, Haruki N, O’Donnell E, Marzolini S, Oh P, Floras JS. Am J Physiol Regul Integr Comp Physiol. 2019 Oct 1;317(4):R503-R512.

Simultaneous assessment of central and peripheral chemoreflex regulation of muscle sympathetic nerve activity and ventilation in healthy young men.
Keir DA, Duffin J, Millar PJ, Floras JS. J Physiol. 2019 Jul;597(13):3281-3296.

Effect of Trendelenburg position and lower-body positive pressure on neck fluid distribution.
Yadollahi A, Singh B, Millar PJ, Vena D, Floras JS, Bradley TD. J Appl Physiol. 2019 May 1;126(5):1259-1264.

Heart Failure-Specific Relationship Between Muscle Sympathetic Nerve Activity and Aortic Wave Reflection.
Millar PJ, Notarius CF, Haruki N, Floras JS. J Card Fail. 2019 May;25(5):404-408.


Comparison of laboratory and ambulatory measures of central blood pressure and pulse wave reflection: hitting the target or missing the mark?
Burns MJ, Seed JD, Incognito AV, Doherty CJ, Notay K, Millar PJ. J Am Soc Hypertens. 2018 Apr;12(4):275-284.

Muscle Strength Influences Pressor Responses to Static Handgrip in Men and Women.
Notay K, Lee JB, Incognito AV, Seed JD, Arthurs AA, Millar PJ. Med Sci Sports Exerc. 2018 Apr;50(4):778-784.

Evidence for Pressure-Independent Sympathetic Modulation of Central Pulse Wave Velocity.
Nardone M, Incognito AV, Millar PJ. J Am Heart Assoc. 2018 Jan 29;7(3). pii: e007971.

2018 Collaborative Papers

Moderate and severe hypoxia elicit divergent effects on cardiovascular function and physiological rhythms.
Allwood MA, Edgett BA, Eadie AL, Huber JS, Romanova N, Millar PJ, Brunt KR, Simpson JA. J Physiol. 2018 Aug;596(15):3391-3410.

Heritability and genetic correlations of heart rate variability at rest and during stress in the Oman Family Study.
Muñoz ML, Jaju D, Voruganti S, Albarwani S, Aslani A, Bayoumi R, Al-Yahyaee S, Comuzzie AG, Millar PJ, Picton P, Floras JS, Nolte I, Hassan MO, Snieder H. J Hypertens. 2018 Jul;36(7):1477-1485.

A comparison of static and dynamic cerebral autoregulation during mild whole-body cold stress in individuals with and without cervical spinal cord injury: a pilot study.
van der Scheer JW, Kamijo YI, Leicht CA, Millar PJ, Shibasaki M, Goosey-Tolfrey VL, Tajima F. Spinal Cord. 2018 May;56(5):469-477.

Heart Rate Variability Responses of Individuals With and Without Saline-Induced Obstructive Sleep Apnea.
Vena D, Bradley TD, Millar PJ, Floras JS, Rubianto J, Gavrilovic B, Perger E, Yadollahi A. J Clin Sleep Med. 2018 Apr 15;14(4):503-510.

Sex Differences in Cardiac Baroreflex Sensitivity after Isometric Handgrip Exercise.
Teixeira AL, Ritti-Dias R, Antonino D, Bottaro M, Millar PJ, Vianna LC. Med Sci Sports Exerc. 2018 Apr;50(4):770-777.

Cortical autonomic network gray matter and sympathetic nerve activity in obstructive sleep apnea.
Taylor KS, Millar PJ, Murai H, Haruki N, Kimmerly DS, Bradley TD, Floras JS. Sleep. 2018 Feb 1;41(2). pii: zsx208.


Acute beetroot juice supplementation on sympathetic nerve activity: a randomized, double-blind, placebo-controlled proof-of-concept study.
Notay K, Incognito AV, Millar PJ. Am J Physiol Heart Circ Physiol. 2017 Jul 1;313(1):H59-H65.

Ischemic preconditioning does not alter muscle sympathetic responses to static handgrip and metaboreflex activation in young healthy men. Incognito AV, Doherty CJ, Lee JB, Burns MJ, Millar PJ. Physiol Rep. 2017 Jul;5(14). pii: e13342.

Commentaries on Viewpoint: Could small-diameter muscle afferents be responsible for the ergogenic effect of limb ischemic preconditioning?
Angius L, Crisafulli A, Hureau TJ, Broxterman RM, Amann M, Incognito AV, Burr JF, Millar PJ, Jones H, Thijssen DJ, Patterson SD, Jeffries O, Waldron M, Silva BM, Lopes TR, Vianna LC, Smith JR, Copp SW, Van Guilder GP, Zuo L, Chuang CC. J Appl Physiol (1985). 2017 Mar 1;122(3):721-725.


Cutaneous Mechanoreceptor Feedback from the Hand and Foot Can Modulate Muscle Sympathetic Nerve Activity. Strzalkowski ND, Incognito AV, Bent LR, Millar PJ. Front Neurosci. 2016 Dec 8;10:568.

Validity and reliability of measuring resting muscle sympathetic nerve activity using short sampling durations in healthy humans.
Notay K, Seed JD, Incognito AV, Doherty CJ, Nardone M, Burns MJ, Millar PJ. J Appl Physiol. 2016 Nov 1;121(5):1065-1073.

Author’s reply to da Mota and Marocolo: “The Effects of Ischemic Preconditioning on Human Exercise Performance: a Counterpoint”.
Incognito AV, Burr JF, Millar PJ. Sports Med. 2016 Oct;46(10):1577-8.

The Effects of Ischemic Preconditioning on Human Exercise Performance.
Incognito AV, Burr JF, Millar PJ. Sports Med. 2016 Apr;46(4):531-44.

Non-invasive electrocardiographic assessments of cardiac autonomic modulation in individuals with spinal cord injury.
Sharif H, Millar PJ, Incognito AV, Ditor DS. Spinal Cord. 2016 Mar;54(3):166-71.

2016 Collaborative Papers

Arousal From Sleep and Sympathetic Excitation During Wakefulness.
Taylor KS, Murai H, Millar PJ, Haruki N, Kimmerly DS, Morris BL, Tomlinson G, Bradley TD, Floras JS. Hypertension. 2016 Dec;68(6):1467-1474.

Isometric exercise training lowers resting blood pressure and improves local brachial artery flow-mediated dilation equally in men and women.
Badrov MB, Freeman SR, Zokvic MA, Millar PJ, McGowan CL. Eur J Appl Physiol. 2016 Jul;116(7):1289-96.

Association between resting-state brain functional connectivity and muscle sympathetic burst incidence.
Taylor KS, Kucyi A, Millar PJ, Murai H, Kimmerly DS, Morris BL, Bradley TD, Floras JS. J Neurophysiol. 2016 Feb 1;115(2):662-73.